Cynthia Burrows, PhD
Cynthia Burrows
Cynthia (Cindy) Burrows is a distinguished professor and faculty member in the Department of Chemistry at the University of Utah. She was the former chair of the Department of Chemistry, recent recipient of the Rosenblatt Prize, and is a faculty member of the Biological Chemistry Program. Her research focuses on nucleic acid chemistry. She investigates the effects of modifications to DNA and RNA bases such as lesion formation and epigenetic effects due to oxidation and the formation of potentially toxic compounds. Her work is pivotal for safety and the future of genetic research. Cynthia is a member of the National Academy of Sciences and the American Academy for Arts and Sciences.
Oral History
To see the two full length interviews conducted with Cynthia, please visit the video for the session on 3/18/21, and its corresponding transcript, along with the video and transcript for the session on 3/23/21.
References
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A.M. Fleming, Y. Ding, C.J. Burrows, Oxidative DNA damage is epigenetic by regulating gene transcription via base excision repair, Proc. Natl. Acad. Sci. U.S.A. 114 (10) 2604-2609, https://doi.org/10.1073/pnas.1619809114 (2017).
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V. Khoddami, A. Yerra, T.L. Mosbruger, A.M. Fleming, C.J. Burrows, B.R. Cairns, Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution, Proc. Natl. Acad. Sci. U.S.A. 116 (14) 6784-6789 https://doi.org/10.1073/pnas.1817334116 (2019).
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Wenchen Luo, James G. Muller, Elliot M. Rachlin, and Cynthia J. Burrows, Characterization of Hydantoin Products from One-Electron Oxidation of 8-Oxo-7,8-dihydroguanosine in a Nucleoside Model, Chemical Research in Toxicology 2001 14 (7), 927-938 https://doi.org/10.1021/tx010072j
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Paul T. Henderson, James C. Delaney, James G. Muller, William L. Neeley, Steven R. Tannenbaum, Cynthia J. Burrows, and John M. Essigmann, The Hydantoin Lesions Formed from Oxidation of 7,8-Dihydro-8-oxoguanine Are Potent Sources of Replication Errors in Vivo, Biochemistry 2003 42 (31), 9257-9262 https://doi.org/10.1021/bi0347252
*Page designed and edited by Noah Garcia. The interview audio, transcript, and bio were written by Marina Gerton, Lydia Hall, Sarita Som and Eva Quintus-Bosz.